Related Experiment Video
Updated: Oct 22, 2025

Investigating Interactions Between Histone Modifying Enzymes and Transcription Factors in vivo by Fluorescence Resonance Energy Transfer
Published on: October 14, 2022
A Novel Epigenetic Regulator ZRF1: Insight into Its Functions in Plants
Jing Feng1, Yahui Gao1, Kun Wang1
1Guangxi Key Laboratory for Polysaccharide Materials and Modifications, School of Marine Sciences and Biotechnology, Guangxi University for Nationalities, Nanning 530008, China.
Abstract:
Recently, Zuotin-related factor 1 (ZRF1), an epigenetic regulator, was found to be involved in transcriptional regulation. In animals and humans, ZRF1 specifically binds to monoubiquitinated histone H2A through a ubiquitin-binding domain and derepresses Polycomb target genes at the beginning of cellular differentiation. In addition, ZRF1 can work as a tumor suppressor. According to bioinformatics analysis, ZRF1 homologs are widely found in plants. However, the current studies on ZRF1 in higher plants are limited and few in-depth studies of its functions have been reported. In this review, we aim to summarize the key role of AtZRF1a/b in Arabidopsis thaliana growth and development, as well as the research progress in this field in recent years.
Related Concept Videos
Cell Signaling in Plants
Transcriptional Regulation: Riboswitches
Riboswitches
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
Master Transcription Regulators
Photoreceptors and Plant Responses to Light
Methods of Nuclear Reprogramming

