Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Contemporary Practices in the Assessment and Management of Climacturia: Results from an International Survey.

European urology open science·2026

Same author

Performance of Artificial Intelligence Chatbots Compared with Young Academic Urologists in Reconstructive Urology.

The French journal of urology·2026

Same author

A multicentre retrospective analysis of anterior urethroplasty techniques and outcomes for urethral stricture disease secondary to transurethral resection of the prostate.

BJUI compass·2026

Same author

Preoperative Bacteriuria and Antimicrobial Resistance in Men Undergoing Urethral Stricture Surgery.

Antibiotics (Basel, Switzerland)·2026

Same author

Effectiveness of contemporary treatments for iatrogenic urethral strictures following endoscopic management of benign prostatic hyperplasia: a comprehensive review.

World journal of urology·2026

Same author

European Association of Urology Guidelines on Urethral Strictures: Summary of the 2026 Guidelines. Update in Recommendations for Endoluminal Management of Male Anterior Urethral Strictures.

European urology·2026

Same journal

Correction: Iliuta et al. Impact of Pulmonary Hypertension on Mortality After Surgery for Aortic Stenosis. <i>Medicina</i> 2022, <i>58</i>, 1231.

Medicina (Kaunas, Lithuania)·2026

Same journal

Prognostic Value of BUN-Based Ratios for Mortality and Prolonged Hospitalization in Acute Upper Gastrointestinal Bleeding: Comparison with Established Risk Scores.

Medicina (Kaunas, Lithuania)·2026

Same journal

One-Year Comparative Outcomes of Conventional Versus Accelerated Corneal Cross-Linking in Progressive Keratoconus.

Medicina (Kaunas, Lithuania)·2026

Same journal

Beyond the Intestinal Mucosa in Long-Standing Inflammatory Bowel Disease: Consequences of Chronic Inflammation and Endoscopic Approaches to Diagnosis and Management.

Medicina (Kaunas, Lithuania)·2026

Same journal

Biological and Metabolic Correlates of Psychological Resilience in Maintenance Hemodialysis: An Exploratory Gender-Based Study.

Medicina (Kaunas, Lithuania)·2026

Same journal

Influence of Mitral Annular Calcification Assessed by Cardiac Computed Tomography on Procedural and Clinical Outcomes of Transcatheter Aortic Valve Implantation.

Medicina (Kaunas, Lithuania)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Oct 22, 2025

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Published on: December 28, 2021

Bladder Cancer: Current Challenges and Future Directions.

Jakub Dobruch¹, Maciej Oszczudłowski¹

¹Centre of Postgraduate Medical Education, Department of Urology, 00-416 Warsaw, Poland.

Medicina (Kaunas, Lithuania)

|August 27, 2021

Summary

This summary is machine-generated.

Bladder cancer (BCa) management is advancing with new treatments and diagnostic tools. Research focuses on improving outcomes and personalized medicine for bladder cancer patients.

Keywords:

BCG failure perioperative chemotherapy surgical treatment urinary bladder cancer

More Related Videos

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Published on: October 30, 2013

Related Experiment Videos

Last Updated: Oct 22, 2025

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Published on: December 28, 2021

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Published on: October 30, 2013

Area of Science:

Urology
Oncology
Cancer Research

Background:

Bladder cancer (BCa) is a prevalent malignancy globally, with historical treatment approaches seeing limited evolution.
Recent advancements signal a transformative period in BCa diagnosis and patient management.
Decreasing BCa mortality correlates with increased awareness of risk factors and reduced carcinogen exposure.

Purpose of the Study:

To review the current status of bladder cancer (BCa) diagnosis and management.
To discuss future directions and emerging trends in BCa research and clinical practice.
To highlight innovations in surgical techniques, therapeutic agents, and personalized medicine.

Main Methods:

Comprehensive literature review of recent advancements in bladder cancer (BCa) research.
Analysis of epidemiological data and trends in BCa incidence and mortality.
Evaluation of novel diagnostic and therapeutic strategies, including surgical, pharmacological, and molecular approaches.

Main Results:

BCa-specific mortality is declining in regions with heightened awareness and reduced carcinogenic exposure.
Refined transurethral surgical techniques and new agents for BCG-failure patients are improving management.
Ongoing trials are challenging the extent of lymphadenectomy in muscle-invasive BCa, with alternatives to perioperative chemotherapy emerging.

Conclusions:

The field of bladder cancer (BCa) is entering an era of personalized medicine, driven by molecular biology insights.
Innovations in diagnosis and management are enhancing oncological outcomes and treatment delivery.
Continued research into epidemiology, diagnosis, and treatment is crucial for advancing bladder cancer (BCa) care.