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Updated: Oct 22, 2025

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
Published on: August 7, 2017
Frequency Domain Repercussions of Instantaneous Granger Causality.
Luiz A Baccalá1, Koichi Sameshima2
1Departamento de Telecomunicações e Controle, Escola Politécnica, Universidade de São Paulo, São Paulo 05508-900, Brazil.
This study unifies instantaneous Granger causality (iGC) with frequency domain methods like directed transfer function (DTF) and partial directed coherence (PDC). Standard models can now detect instantaneous interactions within time series data.
Area of Science:
- Neuroscience
- Information Theory
- Time Series Analysis
Background:
- Directed Transfer Function (DTF) and Partial Directed Coherence (PDC) are established methods for analyzing Granger causality in the frequency domain.
- Existing frameworks may not fully capture instantaneous interactions between time series.
Purpose of the Study:
- To extend the theoretical framework for Granger causality analysis.
- To unify frequency domain methods (DTF, PDC) with instantaneous Granger causality (iGC).
- To provide a comprehensive perspective on directed interactions in time series.
Main Methods:
- Utilized information versions of DTF and PDC.
- Incorporated the frequency domain description of instantaneous Granger causality (iGC).
- Employed standard vector autoregressive (VAR) models.
Main Results:
- Developed a unified theoretical framework for Granger causality analysis.
- Demonstrated that VAR models can represent iGC.
- Showed that instantaneous interactions between time series can be detected using this unified approach.
Conclusions:
- The proposed framework offers a unified perspective on Granger causality in the frequency domain.
- Standard VAR models are capable of portraying instantaneous Granger causality.
- This approach facilitates the detection of non-delayed interactions in time series data.
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