Related Experiment Video
Updated: Oct 22, 2025
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
12.2K
Acute Reperfusion Therapies for Acute Ischemic Stroke
Rajeel Imran1, Ghada A Mohamed1, Fadi Nahab1
1Department of Neurology, Emory University, Atlanta, GA 30322, USA.
Journal of Clinical Medicine
|August 27, 2021
Summary
Recent advancements in acute stroke treatment, including understanding pathophysiology, neuroimaging, and reperfusion therapies, significantly reduce disability. This review highlights progress in reperfusion strategies for acute ischemic stroke.
Area of Science:
- Neurology
- Neurosurgery
- Emergency Medicine
Background:
- Acute stroke treatment has significantly reduced patient disability.
- Understanding pathophysiology, neuroimaging, and reperfusion therapies are key advancements.
Purpose of the Study:
- To review advancements in reperfusion therapies for acute ischemic stroke.
Main Methods:
- Literature review of recent studies on acute ischemic stroke treatment.
- Focus on pathophysiology, neuroimaging, and reperfusion techniques.
Main Results:
- Progress in understanding ischemic injury mechanisms.
- Improved neuroimaging for quantifying stroke extent.
- Development and refinement of acute stroke reperfusion therapies.
Conclusions:
- Reperfusion therapies are crucial for improving outcomes in acute ischemic stroke.
- Continued research in this field promises further reductions in stroke-related disability.
More Related Videos
Related Concept Videos
01:28Acute Coronary Syndrome IV: Interprofessional Care
56
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
56
01:25Cardiopulmonary Resuscitation IV: Pharmacological Management
131
Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
131
01:30Acute Coronary Syndrome I: Introduction
149
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
149
01:27Coronary Artery Disease V: Interprofessional Care
72
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
72
01:29Venous Thrombosis III: Interprofessional Care
65
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
65
01:27Peripheral Artery Disease III: Interprofessional Care
69
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
69