Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cell Lines01:16

Cell Lines

9.0K
A cell line is a population of cells grown in vitro that can be subcultured over several generations. Normal cells cease to divide after a certain number of cell divisions, a process known as replicative senescence. This number, called the Hayflick limit, was conceptualized by Leonard Hayflick in 1961 when he observed that fetal cells grown in culture could only divide 40-60 times. This limit is due to the shortening of the telomeres during each round of cell division, preventing cell division...
9.0K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

76.4K
Overview
76.4K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

6.5K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
6.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rare Taxa and Stochastic Drift Drive the Microbiome Assembly of the Invasive Pest Drosophila suzukii, While Host Filtering Structures the Grape Sour Rot Community.

Microbial ecology·2026
Same author

Microbiome composition and co-occurrence dynamics in wild <i>Drosophila suzukii</i> are influenced by host crop, fly sex, and sampling location.

Microbiology spectrum·2025
Same author

A Head-Specific Transcriptomic Study Reveals Key Regulatory Pathways for Winter Diapause in the Mosquito Culex pipiens.

Archives of insect biochemistry and physiology·2025
Same author

Efficacy and Fate of RNA Interference Molecules in the Green Pea Aphid, Acyrthosiphon pisum.

Archives of insect biochemistry and physiology·2024
Same author

Dietary oxyclozanide influences antioxidant enzyme activities and damages DNA in Galleria mellonella (Lepidoptera: Pyralidae).

Environmental entomology·2024
Same author

A cell line derived from the black soldier fly, Hermetia illucens (Diptera: Stratiomyidae).

In vitro cellular & developmental biology. Animal·2024

Related Experiment Video

Updated: Oct 22, 2025

Generation of Monoclonal Cultures from Wolbachia-infected Drosophila melanogaster JW18 Cell Line
06:09

Generation of Monoclonal Cultures from Wolbachia-infected Drosophila melanogaster JW18 Cell Line

Published on: June 27, 2025

590

Cell Line Platforms Support Research into Arthropod Immunity.

Cynthia L Goodman1, David S Kang1, David Stanley1

  • 1Biological Control of Insects Research Laboratory, USDA/Agricultural Research Service, 1503 S. Providence Rd., Columbia, MO 65203, USA.

Insects
|August 27, 2021
PubMed
Summary

Insect and tick cell lines are vital for studying innate immunity against pathogens. This research uses cell lines to explore invertebrate defense mechanisms, informing pest control strategies.

Keywords:
IMDRNAiTollantimicrobial peptideantiviraleicosanoidhemocyteinnate immunitylysozymepathogensignaling pathway

More Related Videos

Extraction of Hemocytes from Drosophila melanogaster Larvae for Microbial Infection and Analysis
08:54

Extraction of Hemocytes from Drosophila melanogaster Larvae for Microbial Infection and Analysis

Published on: May 24, 2018

12.1K
Thawing, Culturing, and Cryopreserving Drosophila Cell Lines
07:57

Thawing, Culturing, and Cryopreserving Drosophila Cell Lines

Published on: April 16, 2019

81.5K

Related Experiment Videos

Last Updated: Oct 22, 2025

Generation of Monoclonal Cultures from Wolbachia-infected Drosophila melanogaster JW18 Cell Line
06:09

Generation of Monoclonal Cultures from Wolbachia-infected Drosophila melanogaster JW18 Cell Line

Published on: June 27, 2025

590
Extraction of Hemocytes from Drosophila melanogaster Larvae for Microbial Infection and Analysis
08:54

Extraction of Hemocytes from Drosophila melanogaster Larvae for Microbial Infection and Analysis

Published on: May 24, 2018

12.1K
Thawing, Culturing, and Cryopreserving Drosophila Cell Lines
07:57

Thawing, Culturing, and Cryopreserving Drosophila Cell Lines

Published on: April 16, 2019

81.5K

Area of Science:

  • * Invertebrate immunology
  • * Molecular biology
  • * Entomology

Background:

  • * Innate immune responses are crucial for insect and tick health, defending against pathogens like viruses, bacteria, and fungi.
  • * Understanding these defenses is key to controlling medically and agriculturally important arthropod vectors.
  • * Cell line research offers a powerful, high-throughput, and cost-effective method to study invertebrate immunity.

Purpose of the Study:

  • * To review the utility of immortal arthropod cell lines in investigating innate immune responses.
  • * To highlight how cell lines facilitate research into invertebrate defense mechanisms against pathogens.
  • * To discuss future research directions utilizing these cell systems.

Main Methods:

  • * Review of existing literature on arthropod cell lines and innate immunity.
  • * Analysis of case studies demonstrating cell line applications in immunology research.
  • * Discussion of the advantages of using cell lines for high-throughput screening and mechanistic studies.

Main Results:

  • * Cell lines provide a consistent and tractable platform for studying insect and tick immune responses.
  • * Research using cell lines has elucidated various aspects of invertebrate defense against pathogens.
  • * These findings contribute to developing strategies for controlling disease vectors.

Conclusions:

  • * Immortal arthropod cell lines are indispensable tools for advancing our understanding of innate immunity.
  • * Continued research using cell lines will yield critical insights into invertebrate defense mechanisms.
  • * Cell line-based studies are essential for informing effective pest and disease vector control.