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Related Concept Videos

Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-II: Pathophysiology and Classification01:26

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
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Asthma: Pathogenesis and Management01:20

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Asthma-IV: Diagnostic and Management01:30

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Related Experiment Video

Updated: Oct 22, 2025

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
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Electronic Cigarettes and Asthma: What Do We Know So Far?

Serafeim-Chrysovalantis Kotoulas1, Paraskevi Katsaounou2, Renata Riha3

  • 1Clinic of Respiratory Failure, General Hospital of Thessaloniki Georgios Papanikolaou, Aristotle University of Thessaloniki, Leoforos Papanikolaou, 57010 Thessaloniki, Greece.

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Summary

Electronic cigarettes (ECs) may worsen asthma by affecting lung function and inflammation. Asthmatic patients should avoid ECs due to limited smoking cessation effectiveness and potential health risks.

Keywords:
airway inflammationasthmaasthma controlasthma pathogenesiselectronic cigarettelung functionreviewsmoking cessation

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Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
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Area of Science:

  • Pulmonology
  • Respiratory Medicine
  • Toxicology

Background:

  • Electronic cigarettes (ECs) are marketed as tobacco alternatives, but their health effects, particularly in asthma patients, are under-researched.
  • Asthma is a chronic respiratory condition affecting millions worldwide, necessitating careful consideration of environmental and behavioral triggers.

Purpose of the Study:

  • To review existing literature on ECs' impact on asthma pathogenesis.
  • To evaluate ECs' effects on lung function, airway inflammation, and clinical characteristics in asthma patients.
  • To assess ECs' efficacy as a smoking cessation tool for individuals with asthma.

Main Methods:

  • Systematic literature review of studies investigating electronic cigarette use in asthma patients.
  • Analysis of evidence regarding EC compounds and their role in asthma development.
  • Evaluation of data on lung function, inflammatory markers, and clinical outcomes in asthmatic vapers.

Main Results:

  • Many EC compounds may contribute to asthma pathogenesis.
  • EC use appears to impair lung function and alter airway inflammation, notably exacerbating T-helper-type-2 (Th2) responses.
  • ECs may worsen asthma symptoms, exacerbation frequency, and severity, with limited evidence of smoking cessation effectiveness.

Conclusions:

  • Electronic cigarette use poses risks to individuals with asthma, potentially worsening the condition.
  • Asthmatic patients are advised to avoid electronic cigarette use due to adverse respiratory effects and limited cessation benefits.
  • Further research is needed to fully elucidate the long-term respiratory health impacts of ECs in vulnerable populations.