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Updated: Oct 22, 2025

Three-dimensional Optical-resolution Photoacoustic Microscopy
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Breast Acoustic Parameter Reconstruction Method Based on Capacitive Micromachined Ultrasonic Transducer Array.

Yu Pei1, Guojun Zhang1, Yu Zhang1

  • 1State Key Laboratory of Dynamic Testing Technology, North University of China, Taiyuan 030051, China.

Micromachines
|August 27, 2021
PubMed
Summary

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Development of a 1 × 512 Ring Transducer Array-Based 3D Ultrasound Imaging System for Accurate Breast Lesion Detection: Phantom and Preliminary Clinical Feasibility Study.

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This study introduces advanced ultrasound computed tomography (USCT) imaging for breast tissue. New algorithms significantly improve the accuracy of sound speed and attenuation distribution reconstruction in USCT systems.

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Ultrasound Technology

Background:

  • Capacitive micromachined ultrasonic transducer (CMUT) arrays are crucial for ultrasound computed tomography (USCT) systems.
  • Accurate reconstruction of sound speed and acoustic attenuation is vital for effective USCT imaging, particularly in breast tissue analysis.

Purpose of the Study:

  • To develop and validate a high-precision image reconstruction method for CMUT-based USCT systems.
  • To enhance the accuracy of reconstructing sound speed and acoustic attenuation distributions in breast tissue using USCT.

Main Methods:

  • Designed a novel image reconstruction method utilizing the ultrasound propagation path in breast tissue for CMUT ring arrays.
  • Employed time-reversal algorithms for sound speed distribution reconstruction based on wave propagation theory.
Keywords:
CMUT arrayUSCTacoustic attenuationreconstruction methodsound speed

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  • Utilized Filtered Backprojection (FBP) algorithms for acoustic attenuation distribution reconstruction based on ray propagation theory.
  • Verified the method's feasibility through numerical simulations and breast model experiments.

    • Main Results:

    • The time-reversal algorithm reduced sound speed distribution reconstruction deviation by 53.15%.
    • The FBP algorithm reduced attenuation coefficient distribution reconstruction deviation by 61.53%.
    • Demonstrated significant improvements in reconstruction accuracy for both parameters.

    Conclusions:

    • The developed high-precision image reconstruction method offers substantial improvements for USCT systems.
    • This research provides key technological support for the next generation of ultrasound computed tomography systems.
    • The findings highlight the efficacy of combining wave and ray propagation theories for accurate USCT imaging.