Electrophoretically Deposited Chitosan/Eudragit E 100/AgNPs Composite Coatings on Titanium Substrate as a Silver...

Area of Science:

• Biomaterials Science
• Nanotechnology
• Surface Engineering

Background:

• Peri-implant infections pose a significant risk to the longevity of titanium implants.
• Antibacterial coatings are crucial for preventing bacterial colonization and infection.
• Chitosan and Eudragit E 100 offer biocompatible and pH-responsive properties.

Purpose of the Study:

• To fabricate a novel chitosan/Eudragit E 100/silver nanoparticles (chit/EE100/AgNPs) composite coating on titanium grade 2 via electrophoretic deposition (EPD).
• To investigate the influence of deposition parameters (AgNPs content, voltage, time) on coating characteristics.
• To evaluate the antibacterial potential and pH-responsive silver release of the composite coating.

Main Methods:

• Electrophoretic deposition (EPD) was employed to create chit/EE100/AgNPs coatings on titanium grade 2.
• Various characterization techniques were used to analyze morphology, roughness, thickness, composition, wettability, and mechanical properties.
• Electrochemical tests and silver ion release studies at different pH levels were conducted.

Main Results:

• Homogeneous composite coatings were successfully produced, with morphology influenced by deposition parameters.
• The coatings exhibited pH-sensitive behavior, releasing silver ions in reduced pH environments.
• Optimized deposition parameters led to improved coating properties and controlled silver release.

Conclusions:

• The developed chit/EE100/AgNPs composite coating is a promising antibacterial solution for titanium implants.
• The pH-responsive nature of the coating enhances its potential for targeted antibacterial activity.
• EPD is an effective method for producing functionalized coatings with tunable properties for biomedical applications.