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Substituted Pyrazoles and Their Heteroannulated Analogs-Recent Syntheses and Biological Activities
Mohamed Ramadan1, Ashraf A Aly2, Lamiaa E Abd El-Haleem2
1Organic Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assuit 71524, Egypt.
Abstract:
Pyrazoles are considered privileged scaffolds in medicinal chemistry. Previous reviews have discussed the importance of pyrazoles and their biological activities; however, few have dealt with the chemistry and the biology of heteroannulated derivatives. Therefore, we focused our attention on recent topics, up until 2020, for the synthesis of pyrazoles, their heteroannulated derivatives, and their applications as biologically active moieties. Moreover, we focused on traditional procedures used in the synthesis of pyrazoles.
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