Related Experiment Video
Updated: Oct 22, 2025
04:09
Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
3.3K
Associations between Nutrients and Foot Ulceration in Diabetes: A Systematic Review
Nada Bechara1,2,3, Jenny E Gunton2,3,4, Victoria Flood5,6
1Department of Diabetes and Endocrinology, Blacktown-Mt Druitt Hospital, Blacktown, NSW 2148, Australia.
Nutrients
|August 27, 2021
Summary
Poor nutrition correlates with diabetes foot ulcers and delayed healing. More research is needed to confirm if nutritional supplements can improve healing outcomes for diabetic foot ulcer patients.
Area of Science:
- Diabetes management
- Nutritional science
- Wound healing
Background:
- Diabetic foot ulcers (DFUs) are a significant complication of diabetes.
- Nutritional status and interventions may influence DFU presence and healing.
- Evidence linking nutrition to DFUs requires systematic evaluation.
Purpose of the Study:
- To evaluate associations between nutrition and diabetic foot ulceration.
- To assess the impact of nutritional status and interventions on DFU healing.
- To identify gaps in current research regarding nutrition and DFUs.
Main Methods:
- Systematic literature review of studies published before September 2020.
- Searches conducted in Embase, Medline, PubMed, and Cochrane Library.
- Inclusion of 15 studies examining nutritional factors and DFUs.
Main Results:
- A correlation exists between poor nutritional status and DFU presence.
- Delayed healing of diabetic foot ulcers is associated with suboptimal nutrition.
- Causality between nutrition and DFU outcomes remains undetermined.
Conclusions:
- Poor nutritional status is linked to diabetic foot ulceration and impaired healing.
- Insufficient data currently prevents definitive conclusions on causal relationships.
- Further research is necessary to determine the efficacy of nutritional supplementation for DFU healing.
Related Concept Videos
01:26Peripheral Artery Disease IV: Nursing Management
100
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
100
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
76
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
76
01:20Pathophysiology of Diabetes
2.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.1K
01:27Peripheral Artery Disease III: Interprofessional Care
69
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
69
01:23Peripheral Artery Disease V: Postoperative Nursing Management
68
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
68
01:22Diabetes Mellitus: Overview and Type I Subtype
3.9K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
3.9K