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Related Experiment Video

Updated: Oct 22, 2025

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COVID-19 Antibody Tests: An Overview.

Arjun B Ravi1, V P Prabath Singh1, Roshni Chandran2

  • 1Department of Conservative Dentistry and Endodontics, Amrita School of Dentistry, Amrita Vishwa Viyapeetham, Kochi, Kerala, India.

Journal of Pharmacy & Bioallied Sciences
|August 27, 2021
PubMed
Summary

Antibody tests are crucial for understanding COVID-19 spread and immunity. This review details antibody testing for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections.

Keywords:
Antibody testscoronavirus disease 2019serology testssevere acute respiratory syndrome coronavirus-2

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Area of Science:

  • Virology
  • Immunology
  • Epidemiology

Background:

  • Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in late 2019, causing the COVID-19 pandemic.
  • Molecular diagnostic tests are vital but insufficient for comprehensive epidemic response.
  • Growing interest in antibody testing for assessing infection spread and immunity.

Purpose of the Study:

  • To provide an overview of antibody tests for SARS-CoV-2 infections.
  • To highlight the role of serology in complementing molecular diagnostics during the COVID-19 pandemic.

Main Methods:

  • This is a review article, synthesizing existing knowledge on SARS-CoV-2 antibody testing.
  • Focus on the principles and applications of serological assays in the context of COVID-19.

Main Results:

  • Antibody tests confirm past or present SARS-CoV-2 infection.
  • Serology aids in assessing population immunity and herd immunity.
  • Identifies potential donors for convalescent plasma therapy.

Conclusions:

  • Antibody testing is a vital component of the COVID-19 response.
  • Serological assays provide critical data on infection dynamics and immunity.
  • Antibody tests are essential for public health strategies during pandemics.