Remineralization of Artificial Dentin Lesion In vitro using Dental Nanomaterials

Teeth in the human body are the most mineralized tissue, which contain both organic and inorganic components. Demineralization and remineralization of teeth occur continuously, but demineralization causes structural loss of a tooth.

This study was done to find the effect of ceramic by adding mono-n-Dodecyl phosphate to ceramic in dentin remineralization.

A total of sixty permanent intact tooth specimens were randomly divided into four equal groups: Group 1: control group, Group 2: dentin was etched and restored with plain ceramic restoration, Group 3: etched dentin restored with ceramic containing 2% mono-n-Dodecyl phosphate, and Group 4: etched dentin restored with ceramic containing 5% mono-n-Dodecyl phosphate. Each sample was immersed completely in simulated body fluid and was kept in an incubator at 37°C to simulate the human body environment. Knoop microhardness measurements were recorded at 10, 20, and 38 days.

Knoop microhardness of dentin (KHN) reduced to 32.6% after dentin was etched. No significant difference was found between group 2, 3 and 4 after 10 days. KHN value was increased and showed significant changes restored with group 2 and 3, group 3 showed nonsignificant changes.

Through this study, we found that Ceramic can be used as a remineralizing agent to restore marginal dentine around of the cavity and root lesions from secondary caries.