Endovascular papillary angioendothelioma in children

A 15-year-old boy had a tumor in his right thigh of two years' duration. A diagnosis of endovascular papillary angioendothelioma of childhood was made. This condition was first categorized as a low-grade malignancy in 1969, and was called malignant endovascular papillary angioendothelioma of the skin in childhood. Microscopically, the neoplasm is characterized by intravascular proliferation with glomerularlike appearance. The cells are small and regular, with ovoid or round nuclei; some of them show hyperchromasia and pyknosis. For the superficial form we prefer to avoid the use of the word "malignant" due to the usually good prognosis after surgical treatment.