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Knee osteonecrosis after COVID-19

María Angulo-Ardoy1, Álvaro Ureña-Aguilera1

  • 1SERMAS, EAP Adelfas, M.P. Avenida Ciudad de Barcelona, Madrid, Spain.

Family Practice
|August 27, 2021
PubMed

Insights

A COVID-19 survivor developed osteonecrosis, a bone condition, a month after infection. This case highlights the need for careful evaluation of unusual joint pain following SARS-CoV-2 infection.

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Radiology

Background:

  • COVID-19 is an emerging infection with unknown long-term complications.
  • Hypercoagulability is noted in severe cases, but ischemic complications like osteonecrosis are understudied.
  • Previous SARS-CoV1 studies suggested a link to osteonecrosis, possibly due to corticosteroids or the virus itself.

Observation:

  • A 78-year-old woman presented with right knee pain and swelling one month post-COVID-19.
  • Radiography showed no changes, but MRI revealed osteonecrosis of the internal femoral condyle.
  • Blood tests indicated no coagulation abnormalities.

Findings:

  • The patient's osteonecrosis was diagnosed via MRI following COVID-19 infection.
  • No coagulopathy was detected, suggesting a potential direct viral link or other mechanism.
  • Treatment was conservative due to pandemic-related surgical delays.

Implications:

  • This case suggests a potential association between COVID-19 and osteonecrosis.
  • Unusual joint pain after COVID-19 warrants thorough investigation.
  • Further research is needed to understand the mechanisms and long-term effects of COVID-19 on bone health.
Abstract

Keywords:
COVID-19CorticosteroidsSARS-CoV1hypercoagulabilityjoint painosteonecrosis

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