Related Experiment Video

Updated: Oct 22, 2025

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

10.6K

Asthma and risk factors in the first 6 years of life in a population-based cohort

Ayşe Şenay Şaşihüseyinoğlu1, Dilek Özcan1, Derya Ufuk Altıntaş1

  • 1Department of Pediatric Allergy and Immunology, Çukurova University Faculty of Medicine, Adana, Turkey.

The Turkish Journal of Pediatrics
|August 27, 2021
PubMed

Insights

Childhood asthma prevalence was assessed up to age six. Maternal antibiotic use during pregnancy, parental allergies, and early wheezing were key risk factors for pediatric asthma.

Area of Science:

  • Pediatric Allergy and Immunology
  • Respiratory Medicine
  • Epidemiology

Background:

  • Asthma prevalence increases in childhood, with age-specific risk factors.
  • Understanding early-life risk factors is crucial for pediatric asthma management.

Purpose of the Study:

  • To determine the prevalence of asthma in children up to six years of age.
  • To identify associated risk factors for asthma development in early childhood.

Main Methods:

  • The Adana Pediatric Allergy and Risk Factor (ADAPAR) birth cohort study followed 203 infants with early wheezing and 223 controls until age six.
  • Asthma diagnosis was confirmed at the end of the sixth year.

Main Results:

  • Asthma was diagnosed in 22.7% of children by age six.
  • Significant risk factors included maternal antibiotic use during pregnancy (OR: 2.98), maternal allergies (OR: 4.70), sibling allergies (OR: 2.11), atopy (OR: 4.76), and recurrent early wheezing (OR: 17.35).

Conclusions:

  • The study found a higher asthma prevalence at six years compared to other studies.
  • Preventing early-life and prenatal infections may reduce pediatric asthma rates.
Abstract

Keywords:
asthmachildhoodrisk factorwheezing

More Related Videos

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.1K
Methodology for Sputum Induction and Laboratory Processing13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

28.0K

Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.9K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
855
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
3.4K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
2.7K
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
3.4K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.7K