Related Experiment Video
Updated: Oct 22, 2025

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
Published on: October 3, 2019
Serum Sickness-Like Reaction in an Adolescent Taking Minocycline for Acne
Christopher T Lucido1, Jana Johnson2,1
1University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
Abstract:
We report a case of serum sickness-like reaction (SSLR) in a 14-year-old male taking minocycline for acne. The patient presented with urticarial rash, arthralgia/arthritis, and tender lymphadenopathy. Symptoms resolved with discontinuation of minocycline and treatment with prednisone, cetirizine, and ibuprofen. SSLR is a rare complication of minocycline treatment that may go unrecognized and underreported.
Related Concept Videos
Allergic Drug Reactions
Allergic Reactions
Antiasthma Drugs: Leukotriene Modifiers
Leukotriene modifiers work through two distinct mechanisms:

