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[Karyotype in fortuitous familial meningioma. Report of 2 cases]
M Acqui1, L Mastronardi, L Ferrante
1Dipartimento di Scienze Neurologiche, Cattedra di Neurochirurgia II, Università La Sapienza, Roma.
Abstract:
The authors report a case of two sisters affected of intracranial meningioma, with no evidence of von Recklinghausen's disease. A study of the karyotype has been performed in the patients and in their family; in one sister we have found a pericentric inversion of one chromosome 9. The possible role of the chromosomal abnormality in the develop of familial meningioma is discussed.