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Updated: Oct 22, 2025

Tick Microbiome Characterization by Next-Generation 16S rRNA Amplicon Sequencing

Tick Microbiome Characterization by Next-Generation 16S rRNA Amplicon Sequencing

Published on: August 25, 2018

Priority effects in microbiome assembly.

Reena Debray¹, Robin A Herbert^2,3, Alexander L Jaffe⁴

¹Department of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA. rrdebray@berkeley.edu.

Nature Reviews. Microbiology

|August 28, 2021

Summary

This summary is machine-generated.

Microbial communities are shaped by historical events, like the arrival order of species (priority effects). Understanding these effects is key to managing microbiomes for ecological function and health.

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Area of Science:

Microbiology
Ecology
Systems Biology

Background:

Next-generation sequencing enables extensive microbiome analysis.
Deterministic factors of community composition are known, but historical contingency is not.
Priority effects, where arrival order influences species establishment, are poorly understood in microbial systems.

Purpose of the Study:

To review mechanisms and evidence of priority effects in microbial communities.
To describe methods for testing and predicting priority effects.
To discuss implications for microbiome management.

Main Methods:

Literature review of priority effect mechanisms and evidence.
Description of approaches for testing and prediction.
Re-analysis of public microbiome datasets (plant and animal).

Main Results:

Priority effects are important across diverse environments (gut, soil, oceans, etc.).
Shared principles of eco-evolutionary dynamics and scale emerge.
Predicting arrival order impacts is crucial for microbiome management.

Conclusions:

Priority effects significantly influence microbial community assembly and function.
Management of microbiomes requires understanding historical contingency.
Challenges remain in measuring priority effects in complex microbial systems.