International consensus on the use of [18F]-FDG PET/CT in pediatric patients affected by epilepsy

Mei Tian1,2, Yasuyoshi Watanabe3, Keon Wook Kang4

  • 1Department of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China. meitian@zju.edu.cn.

Insights

This international consensus provides the first guideline for using 18F-fluorodeoxyglucose (FDG) PET/CT scans in children with epilepsy. It standardizes the precise localization of the epileptogenic focus in pediatric epilepsy patients.

Area of Science:

  • Nuclear Medicine
  • Pediatric Neurology
  • Medical Imaging

Background:

  • 18F-fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) is crucial for localizing the epileptogenic focus in epilepsy patients.
  • Its application is expanding, particularly in pediatric epilepsy cases.

Purpose of the Study:

  • To establish the first international consensus and practice guideline for brain 18F-FDG PET/CT in pediatric epilepsy.
  • To provide specific considerations for utilizing 18F-FDG PET in pediatric epilepsy patients.

Main Methods:

  • An international, multidisciplinary task group was formed to develop the guideline.
  • The guideline covers clinical indications, patient preparation, radiopharmaceuticals, image acquisition, processing, interpretation, and reporting.

Main Results:

  • The guideline for brain 18F-FDG PET/CT in pediatric epilepsy patients has been discussed and approved.
  • This consensus establishes an international standard for clinical practice.

Conclusions:

  • This document represents the first international consensus and practice guideline for brain 18F-FDG PET/CT in pediatric epilepsy.
  • It aims to standardize and improve the clinical application of 18F-FDG PET/CT for pediatric epilepsy management.
Abstract