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Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
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[Cardiac metastasis from primary anaplastic thyroid carcinoma]
Tomás F Cianciulli1, Laura V Argento1, María C Saccheri1
1División Cardiología, Hospital General de Agudos Dr. Cosme Argerich, Buenos Aires, Argentina.
Medicina
|August 28, 2021
Summary
Cardiac metastasis is more common than primary tumors. This report details two cases of anaplastic thyroid carcinoma spreading to the heart, highlighting underdiagnosis challenges.
Area of Science:
- Oncology
- Cardiology
- Pathology
Background:
- Cardiac neoplasms are rare, with metastatic tumors being far more common than primary cardiac tumors.
- Metastatic cardiac involvement is 20-40 times more frequent than primary cardiac tumors, accounting for 95% of all cardiac tumors.
- Cardiac tumors are often underdiagnosed due to subtle clinical and oncologic features.
Observation:
- This report presents two cases of cardiac metastasis originating from primary anaplastic thyroid carcinoma.
- A 69-year-old woman presented with metastasis to the right ventricle.
- A 61-year-old man was diagnosed with metastasis to the right atrium.
Findings:
- Both patients with cardiac metastasis from anaplastic thyroid carcinoma died during hospitalization.
- One of the cases underwent an autopsy, providing further pathological insights.
- Anaplastic thyroid carcinoma can present with cardiac metastasis, contributing to diagnostic challenges.
Implications:
- Increased awareness of cardiac metastasis from anaplastic thyroid carcinoma is crucial for timely diagnosis and management.
- Further research into the mechanisms and clinical presentation of cardiac metastasis is warranted.
- Autopsy findings can be invaluable in understanding the full extent and impact of cardiac metastatic disease.
