[Dhori virus--a causative agent of human disease. 5 cases of laboratory infection]

The materials presented in the paper are first indications of the pathogenicity of Dhori virus for man and prove the role of this agent in the occurrence of 5 cases of the disease in laboratory workers accidentally infected during the preparation of cultural agents. Clinically, Dhori infection was characterized by an acute course with marked general toxicity and a febrile period of 2 to 4 days. Two out of 5 patients had changes on the part of the nervous system of the type of encephalitic reaction predominantly with subcortical symptoms and mild involvement of the pyramidal system or in the form of encephalopolyradiculoneuritis with paresthesia and sensitivity disorders.