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Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
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Trends and outcomes of chronic coronary total occlusion-related ventricular tachyarrhythmias

Upenkumar Patel1, Mohammed Zubair1, Rezwan Munshi1

  • 1Department of Internal Medicine, Nassau University Medical Center, East Meadow, New York.

Proceedings (Baylor University. Medical Center)
|August 30, 2021
PubMed

Insights

Ventricular tachyarrhythmia (VTA) in chronic coronary total occlusion (CCTO) patients is increasing and linked to worse outcomes. This includes higher mortality, longer hospital stays, and increased complications like cardiogenic shock.

Area of Science:

  • Cardiology
  • Inpatient Health Outcomes
  • Epidemiology

Background:

  • Chronic coronary total occlusion (CCTO) represents a significant clinical challenge.
  • Ventricular tachyarrhythmia (VTA) is a serious complication in cardiovascular disease.
  • Understanding VTA trends in CCTO is crucial for patient management.

Purpose of the Study:

  • To determine the incidence and temporal trends of VTA in patients with CCTO.
  • To evaluate the association between VTA and clinical outcomes in CCTO patients.
  • To analyze resource utilization associated with VTA in CCTO hospitalizations.

Main Methods:

  • Retrospective analysis of the National Inpatient Sample database.
  • Identification of CCTO hospitalizations with and without VTA.
  • Statistical analysis to compare outcomes and trends between groups.

Main Results:

  • 10.1% of 911,579 CCTO hospitalizations were associated with VTA.
  • The CCTO-VTA cohort experienced higher all-cause mortality (aOR=4.45), longer hospital stays, and increased hospital charges.
  • VTA was linked to higher rates of cardiogenic shock, venous thromboembolism, respiratory failure, and mechanical ventilation.

Conclusions:

  • VTA occurrence in CCTO patients is associated with significantly worse clinical outcomes and increased healthcare resource utilization.
  • There was a notable increase in VTA and all-cause mortality among CCTO patients between 2010 and 2014.
  • Interventional procedures like PCI and CABG showed increasing trends in VTA occurrence.

Keywords:
Chronic coronary total occlusioncoronary artery diseaseventricular tachyarrhythmias

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