Related Experiment Video
Updated: Oct 22, 2025
06:15
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
1.5K
Devastating effect of untreated facial squamous cell carcinoma
Nasim Khalfe1, Ya Xu2, Elizabeth May Schuele2
1Baylor College of Medicine, Houston, Texas.
Proceedings (Baylor University. Medical Center)
|August 30, 2021
Summary
Delayed treatment for squamous cell carcinoma (SCC) can lead to severe outcomes. This case highlights the aggressive progression of facial SCC, including perineural invasion and lymph node metastasis, due to delayed medical care.
Area of Science:
- Dermatology
- Oncology
Background:
- Squamous cell carcinoma (SCC) is a common skin cancer, typically curable when detected early.
- Sun-exposed skin is the primary site for SCC development.
Observation:
- A 57-year-old man presented with a significantly large facial squamous cell carcinoma.
- The patient experienced delays in accessing timely medical treatment.
Findings:
- The advanced facial SCC demonstrated perineural invasion.
- Metastasis to the parotid lymph nodes was observed.
- Delayed treatment was the primary factor contributing to the advanced disease state.
Implications:
- This case underscores the critical importance of early diagnosis and prompt treatment for skin cancers.
- Advanced SCC with perineural invasion and metastasis presents significant therapeutic challenges.
- Timely access to healthcare is crucial for preventing severe morbidity and mortality from skin cancer.
More Related Videos
Related Concept Videos
01:30Skin Cancer
4.9K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.9K
01:12Loss of Tumor Suppressor Gene Functions
5.3K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
When the tumor suppressor genes develop mutations or are lost, cells start growing out of control, leading to cancer. However, a single functional copy of the tumor suppressor gene is enough for the cells to maintain their normal functions and cell...
When the tumor suppressor genes develop mutations or are lost, cells start growing out of control, leading to cancer. However, a single functional copy of the tumor suppressor gene is enough for the cells to maintain their normal functions and cell...
5.3K
02:56Treatment Resistant Cancers
3.4K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.4K