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Updated: Oct 22, 2025

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
Published on: January 3, 2025
Targeting Cis-Regulatory Elements for Rice Grain Quality Improvement
Yu Ding1, Jiannan Zhu1, Dongsheng Zhao1
1Key Laboratory of Plant Functional Genomics of the Ministry of Education, Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding, Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, Jiangsu Key Laboratory of Crop Genetics and Physiology, College of Agriculture, Yangzhou University, Yangzhou, China.
Cis-regulatory elements (CREs) are key to improving rice grain quality. Genome editing of CREs offers a precise strategy for enhancing rice nutritional value and yield potential.
Area of Science:
- Plant genetics and breeding
- Molecular biology
- Agricultural science
Background:
- Rice is a global staple, making its grain quality crucial for food security.
- Grain quality is a complex trait influenced by genetics and environment, a key focus for breeders.
- Cis-regulatory elements (CREs) control gene expression and offer precise gene modification potential.
Purpose of the Study:
- To review recent findings on CREs related to rice grain quality.
- To highlight CREs as targets for genome editing in rice improvement.
- To discuss challenges and considerations for applying CRE modifications in crops.
Main Methods:
- Literature review of studies on CRE identification, characterization, and application.
- Analysis of genome editing technologies for modifying plant genes.
- Discussion of strategies for enhancing rice grain quality traits.
Main Results:
- CREs play a critical role in regulating gene expression for rice grain quality.
- Genome editing enables precise modification of CREs to fine-tune gene expression.
- CREs are identified as promising targets for genetic improvement of rice.
Conclusions:
- Cis-regulatory elements are valuable targets for genome editing to improve rice grain quality.
- Targeting CREs allows for fine-tuning gene expression and creating allelic diversity.
- Further research and experimental considerations are needed for successful application in crop improvement.
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