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Updated: Oct 22, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Unicentric Castleman disease in the mesentery with ambiguous symptoms: a rare case report
Lama Kadoura1, Amr Hamza2, Afnan W M Jobran3
1Department of Surgery, Aleppo University Hospital, Aleppo, Syria.
Abstract:
Castleman disease (CD) is a rare clinical entity characterized by enlarged lymph nodes. It may affect a single lymph node (unicentric) or multiple lymph nodes in the body (multicentric). However, it is exceptionally uncommon for unicentric Castleman disease (UCD) to present in the mesentery. Herein, we report a case of 38-year-old female complaining of polymenorrhea and abdominal discomfort for 4 months. Her past medical history was unremarkable; however, she has started smoking recently. The physical examination and radiography indicated a large, well-defined mass in the right hypochondrium. Eventually, the patient underwent laparotomy and the mass was excised totally. The Pathologic study confirmed the diagnosis as mesenteric CD, hyaline-vascular type. After 5 months of follow-up, the patient showed no evidence of recurrence. In conclusion, this case underscores the importance of taking mesenteric CD into consideration in each patient who presents with solid abdominal mass or ambiguous abdominal discomfort.
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