pH-Responsive DNA Motif: From Rational Design to Analytical Applications

Lin Lin Zheng1, Jin Ze Li1, Ying Xu Li1

  • 1Shandong Province Key Laboratory of Detection Technology for Tumor Makers, Collaborative Innovation Center of Tumor Marker Detection Technology, School of Chemistry and Chemical Engineering, Feixian Campus, Linyi University, Linyi, China.

Frontiers in Chemistry
|August 30, 2021
PubMed
Summary

pH-responsive DNA motifs are highly versatile due to their designability. This review covers DNA secondary structures like triplex DNA and i-motifs that respond to pH changes, discussing future prospects.