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Updated: Oct 22, 2025

Human Colonoid Monolayers to Study Interactions Between Pathogens, Commensals, and Host Intestinal Epithelium
Published on: April 9, 2019
COMPERATIVE STRUCTURE OF MUCOSA COAT OF THE PIG`S AND THE HUMAN`S RECTUM
Roman О Plakhotnyi1, Іryna V Кerechanyn1, Larysa Ya Fedoniuk2
1PRIVATE HIGHER EDUCATIONAL ESTABLISHMENT «KYIV MEDICAL UNIVERSITY», KYIV, UKRAINE.
Objective:
The aim: To determine whether the pig could be used as biomodel for study and reconstruction of rectal pathology for development the new approaches for prevention and treatment of rectal diseases.
Patients And Methods:
Materials and methods: For the research the rectum of 8 vietnamese pot-bellied pigs were used. Via macro- and microscopy the structure of mucosa coat of the pig`s and human`s rectum was compared.
Results:
Results: Mucosa coat`s peculiarities of pig`s and human`s rectum in comparative aspect are described in this article. With the help of traditional methods, known as macroscopy the structure of the pig`s rectal mucosa was study and compared wih macrostructure of human`s rectum. The microstucture of pig`s rectal mucosa was study due to histological method too. The macro- and microscopy demonstrated that structure of pig`s and human`s rectal mucosa are similar and includes same structural components.
Conclusion:
Conclusions: Thus, the research proved that pigs can be used as biomodels in biomedical research for creating various new methods and applications in approaching the prevention and treatment of rectal pathology in humans.
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