Related Experiment Video

Updated: Oct 22, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

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[Familial hemiplegic migraine]

N L Starikova1, A A Kulesh1

  • 1Vagner Perm State Medical University, Perm, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|August 30, 2021
PubMed

Insights

Familial hemiplegic migraine (FHM) is a rare neurological disorder. This case study details a family diagnosed with FHM, highlighting its characteristic motor and aura symptoms for better understanding and diagnosis.

Area of Science:

  • Neurology
  • Genetics

Background:

  • Hemiplegic migraine (HM) is a rare migraine subtype (0.01% prevalence) characterized by motor deficits (hemiparesis) and typical migraine aura symptoms.
  • Familial hemiplegic migraine (FHM) is diagnosed when first- or second-degree relatives also experience HM attacks.

Purpose of the Study:

  • To describe a family diagnosed with Familial Hemiplegic Migraine (FHM).
  • To review literature and discuss differential diagnosis aspects of FHM.

Main Methods:

  • Clinical case report.
  • Review of medical literature.

Main Results:

  • A father and daughter presented with severe headaches, nausea, vomiting, visual disturbances, speech impairment, and unilateral weakness/numbness.
  • The clinical presentation and family history led to a diagnosis of FHM.

Conclusions:

  • The described family case supports the diagnostic criteria for FHM.
  • Understanding FHM presentation is crucial for accurate diagnosis and management.
Keywords:
familialhemiplegicmigraine

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