Related Experiment Video
Updated: Oct 22, 2025

Robotic Ablation of Atrial Fibrillation
Published on: May 29, 2015
Adenosine revives catheter-induced mechanical blocks in radiofrequency ablation
Keita Tsukahara1, Yasushi Oginosawa1, Keishiro Yagyu1
1The Second Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Abstract:
Adenosine can hyperpolarize the atrial action potential, which helps rapidly re-establish the membrane potential in ablated sites and unmask "dormant conduction." It has been reported that pharmacological agents, including adenosine, were unable to revive traumatized tissues. We present the first case of the catheter-induced mechanical block ("bump" phenomenon) that was unmasked with adenosine administration in the working myocardium of the superior vena cava. This result may be because, unlike before, we could determine the force of contact between the tip of the ablation catheter and the myocardial tissue. This case suggests the clinical usefulness of adenosine for unmasking bumped sites.
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