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Updated: Oct 22, 2025

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Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples
Published on: January 13, 2023
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Liquid Biopsy for Cancer Detection: Clinical and Epidemiologic Considerations
Nicolas Wentzensen1, Megan A Clarke2
1Clinical Epidemiology Unit, Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, NCI, NIH, Rockville, Maryland. wentzenn@mail.nih.gov.
Abstract:
Detection of circulating nucleic acids, also referred to as liquid biopsy, has been evaluated for detection of cancer in a variety of settings. We describe important clinical and epidemiologic considerations for liquid biopsy applications in cancer early detection and for monitoring of cancer recurrence.See related article by Jeannot et al., p. 5869.

