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Stage 4 Takayasu Retinopathy With Persistent Neovascularization.
Siti Amra Abd Rahman1, Safinaz Mohd Khialdin1, Rosiah Muda2
1Ophthalmology, Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.
Cureus
|August 31, 2021
Summary
Takayasu arteritis can cause severe vision loss, as seen in a case of stage 4 Takayasu retinopathy. This condition proved resistant to standard treatments, including pan-retinal photocoagulation, highlighting challenges in managing ocular complications.
Area of Science:
- Ophthalmology
- Rheumatology
- Vascular Medicine
Background:
- Takayasu arteritis is a rare autoimmune disease affecting large blood vessels.
- Ocular complications, such as Takayasu retinopathy, can lead to significant visual impairment.
- Management of advanced retinopathy in Takayasu arteritis remains challenging.
Observation:
- A 22-year-old woman with Takayasu arteritis presented with symptoms of claudication and hypertension.
- Ophthalmological examination revealed progressive Takayasu retinopathy, advancing to stage 4 with proliferative changes.
- The patient exhibited poor compliance with immunomodulatory therapy.
Findings:
- Despite conventional treatments including pan-retinal photocoagulation and immunosuppression, the patient's proliferative retinopathy showed no regression.
- The case illustrates the potential for rapid progression of Takayasu retinopathy.
- Treatment resistance underscores the need for novel therapeutic strategies.
Implications:
- This case highlights the critical need for vigilant monitoring of ocular health in Takayasu arteritis patients.
- Poor compliance significantly impacts treatment efficacy for both systemic and ocular manifestations.
- Further research into advanced treatment options for refractory Takayasu retinopathy is warranted.
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