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The Relationship Between Vitamin D and Asthma Exacerbation.
Opemipo D Ogeyingbo1,2,3, Rowan Ahmed4, Mallika Gyawali4
1Research, California Institute of Behavioral Neurosciences & Psychology (CIBNP), Fairfield, USA.
Cureus
|August 31, 2021
Summary
Low vitamin D levels are common in asthma exacerbations. Supplementation may help reduce asthma flare-ups, particularly in adults with vitamin D deficiency.
Area of Science:
- Pulmonary Medicine
- Nutritional Science
- Immunology
Background:
- Asthma is a chronic airway inflammatory disease characterized by reversible bronchoconstriction.
- Asthma exacerbations, which can be severe and life-threatening, are linked to inflammation and epithelial changes.
- Vitamin D, a steroid-derived vitamin, plays a role in calcium regulation, bone health, and immune modulation.
Purpose of the Study:
- To investigate the relationship between vitamin D levels and asthma exacerbation.
- To determine if vitamin D supplementation impacts asthma exacerbation rates.
Main Methods:
- Literature review of articles from PubMed and CINAHL Plus databases.
- Analysis of studies examining vitamin D levels in asthmatic patients during exacerbations.
- Evaluation of the efficacy of vitamin D supplementation in reducing asthma exacerbation rates.
Main Results:
- Asthmatic patients frequently exhibit low vitamin D levels during exacerbations.
- Vitamin D supplementation did not consistently reduce asthma exacerbation rates across all populations studied.
- Supplementation showed potential benefit in adult asthmatic patients with pre-existing vitamin D deficiency.
Conclusions:
- Low vitamin D levels are associated with asthma exacerbations.
- Vitamin D supplementation may be beneficial for specific subgroups, such as vitamin D-deficient adults with asthma.
- Further research is needed to clarify the role of vitamin D in asthma management.
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