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Implications of new clinical practice guidance on familial hypercholesterolaemia for Australian general practitioners

Tom Brett1, Jan Radford2, Clare Heal3

  • 1MA, MD, FRACGP, MRCGP, Professor and Director, General Practice and Primary Health Care Research, School of Medicine, University of Notre Dame, Fremantle, WA; General Practitioner, Mosman Park Medical Centre, Mosman Park, WA.

Australian Journal of General Practice
|August 31, 2021
PubMed

Insights

Familial hypercholesterolaemia (FH), a genetic lipid disorder, is often missed. This review guides Australian GPs on FH identification and management, utilizing new genetic testing and PCSK9 inhibitor support.

Area of Science:

  • Cardiology
  • Genetics
  • Primary Care Medicine

Background:

  • Familial hypercholesterolaemia (FH) is a monogenic lipid disorder.
  • FH diagnosis is often overlooked in routine clinical practice.
  • This review focuses on FH identification and management challenges for Australian general practitioners (GPs).

Purpose of the Study:

  • To review key areas for FH identification and management relevant to Australian GPs.
  • To highlight recent consensus advice and new support mechanisms for FH care.
  • To emphasize the importance of enhanced GP awareness and skills in diagnosing and managing FH.

Main Methods:

  • Review of recent Australian consensus advice on FH care.
  • Examination of new Medicare Benefits Schedule items for genetic testing.
  • Analysis of Pharmaceutical Benefits Scheme listing for PCSK9 inhibitors.

Main Results:

  • New support items facilitate genetic testing and PCSK9 inhibitor use for FH patients.
  • A shared-care model with specialists is recommended for optimal FH management.
  • Implementation of FH guidance in primary care presents ongoing challenges.

Conclusions:

  • Australian GPs are presented with opportunities to improve FH diagnosis and management.
  • Enhanced awareness, skills, and utilization of new support systems are crucial.
  • A collaborative, multidisciplinary approach is essential for effective FH care and improved patient outcomes.
Abstract

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