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Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

535
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
535
Pneumothorax-II01:27

Pneumothorax-II

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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
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Related Experiment Video

Updated: Oct 22, 2025

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
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Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis.

Junfeng Han1, Long Yuan2, Jianguo Li2

  • 1Tuberculosis Department, TCM Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Haihe Hospital, Tianjin, China.

The Journal of International Medical Research
|August 31, 2021
PubMed
Summary

Transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy significantly improves cavity closure and sputum negativity in patients with cavitary pulmonary tuberculosis, showing a higher success rate and no recurrence compared to drug therapy alone.

Keywords:
Transbronchial tuberculosis cavity pluggingcavitary pulmonary tuberculosiscavity closurenegative sputumprognosistreatment success rate

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Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Interventional Radiology

Background:

  • Cavitary pulmonary tuberculosis presents a significant treatment challenge.
  • Standard drug therapy alone may have limitations in achieving complete cavity closure.

Purpose of the Study:

  • To evaluate the efficacy and safety of transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy for cavitary pulmonary tuberculosis.
  • To compare outcomes of combined therapy versus drug therapy alone.

Main Methods:

  • A comparative study involving 260 patients with cavitary tuberculosis from 2012 to 2018.
  • Observation group: TTCP combined with drug therapy (n=130).
  • Control group: Drug therapy alone (n=130).
  • Assessed cavity size, sputum conversion, treatment success, and recurrence rates.

Main Results:

  • Higher rates of cavity closure observed in the TTCP group compared to the control group.
  • Significantly higher proportion of negative sputum samples in the observation group.
  • Treatment success rate of 98.46% in the TTCP group versus 92.3% in the control group.
  • No recurrence in the TTCP group, compared to 8.3% in the control group.

Conclusions:

  • Transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy is an effective treatment for cavitary pulmonary tuberculosis.
  • This combined approach demonstrates improved cavity closure, higher treatment success, and reduced recurrence.
  • TTCP shows good outcomes with limited side effects and minimal complications.