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Updated: Oct 22, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Evidence-based practice knowledge, attitudes, practices, and barriers
Jane Crable1, Martha E Farrar Highfield, Frances Patmon
1Jane Crable is the senior director of nursing at Mercy General Hospital in Sacramento, Calif.; Martha E. Farrar Highfield is a professor emeritus at California State University, Northridge, in Northridge, Calif.; and Frances Patmon is director of emergency services at Mercy Hospital of Folsom in Folsom, Calif.
Abstract:
This study assessed nurses' knowledge, attitudes, practices, and perceived barriers related to evidence-based practice (EBP). Nurses reported highly positive attitudes toward EBP, and relatively strong EBP knowledge and practices, but they also identified several barriers. Removing barriers and building on strengths may close this knowledge-practice gap.
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