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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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[Update on diagnostics and treatment of heart failure]

Jan Wintrich1, Ann-Kathrin Berger2, Yvonne Bewarder2

  • 1Klinik für Innere Medizin III - Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrbergerstraße, 666421, Homburg/Saar, Deutschland. Jan.Wintrich@uks.eu.

Herz
|August 31, 2021
PubMed

Insights

Heart failure is rising globally, with high mortality rates despite advances. Guideline-conform diagnostics and treatment are crucial for managing this growing challenge.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Global incidence and prevalence of heart failure are increasing.
  • High mortality and morbidity rates persist despite scientific and clinical innovations.
  • Cardiac decompensation is a leading cause of hospital admissions in Germany.

Purpose of the Study:

  • To review the latest scientific knowledge on acute and chronic heart failure.
  • To emphasize the importance of guideline-conform diagnostics and treatment.
  • To address the challenges heart failure poses to the German healthcare system.

Main Methods:

  • Literature review of scientific knowledge published between 2018-2020.
  • Focus on acute and chronic heart failure.
  • Analysis of diagnostic and treatment guidelines.

Main Results:

  • Despite innovations, heart failure outcomes remain suboptimal.
  • Guideline-conform approaches are critical for effective management.
  • Heart failure treatment presents a significant challenge to healthcare systems.

Conclusions:

  • Continuous updates in scientific knowledge are essential for improving heart failure care.
  • Adherence to established guidelines is paramount for reducing mortality and morbidity.
  • Addressing heart failure requires a comprehensive and system-wide approach.

Keywords:
Cardiac decompensationHeart failureLCZ696Sodium-glucose transporter 2 inhibitorsVericiguat

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