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Peptide Kappa Opioid Receptor Ligands and Their Potential for Drug Development

Jane V Aldrich1, Jay P McLaughlin2

  • 1Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, USA. janealdrich@ufl.edu.

Handbook of Experimental Pharmacology
|August 31, 2021
PubMed

Keywords:
All D-amino acid tetrapeptidesAnalgesiaBlood brain barrier permeabilityCJ-15,208DynorphinKappa opioid receptorMacrocyclic tetrapeptidesMood disordersOral activityPeripherally restricted ligandPruritusRespirationStressSubstance abusecyclo[Pro-Sar-Phe-D-Phe]

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