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Vitamin D deficiency among Polish patients with angiographically confirmed coronary heart disease

Ewelina A Dziedzic1, Jakub S Gąsior2, Tomasz Saniewski3

  • 1Faculty of Medicine, the Lazarski University of Warsaw, Poland.

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|August 31, 2021
PubMed

Insights

Ninety-four percent of Polish patients with coronary artery disease have vitamin D deficiency, with 22% experiencing severe deficiency. These findings highlight the need for strategies to address vitamin D levels in this population.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • Limited epidemiological data exists on serum vitamin D levels in Polish patients diagnosed with coronary artery disease (CAD).
  • Vitamin D plays a role in cardiovascular health, and CAD remains a leading cause of death globally.
  • Addressing vitamin D deficiency is crucial for managing cardiovascular risk.

Purpose of the Study:

  • To prospectively evaluate vitamin D concentrations in Polish patients undergoing coronary angiography for suspected CAD.
  • To determine the prevalence of vitamin D deficiency and its severity in this patient cohort.

Main Methods:

  • A prospective study included 1,043 patients (374 women, 669 men; mean age 66.9 years) undergoing coronary angiography between 2013-2017.
  • Plasma 25(OH)D concentrations were measured using electrochemiluminescence.
  • Patients were categorized based on vitamin D levels: optimal (≥30 ng/ml), mild deficiency (20-29.9 ng/ml), moderate deficiency (10-19.9 ng/ml), and severe deficiency (<10 ng/ml).

Main Results:

  • The median 25(OH)D concentration was 15.2 ng/ml.
  • Vitamin D deficiency was prevalent in 94% of the study population.
  • Optimal vitamin D levels were observed in only 6% of patients.
  • Severe deficiency (<10 ng/ml) affected 22% of patients, while moderate and mild deficiencies were found in 50% and 22%, respectively.

Conclusions:

  • A high prevalence of vitamin D deficiency (94%) exists among Polish patients with angiographically confirmed coronary artery disease.
  • A significant proportion (22%) exhibit severe vitamin D deficiency.
  • Prophylactic and therapeutic interventions targeting vitamin D deficiency are recommended for this high-risk population in Poland.

Keywords:
coronary artery diseasevitamin D

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