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Published on: November 10, 2023
Survival Rates and Prognostic Factors in Patients with Coronavirus Disease 2019: A Registry-Based Retrospective
Fatemeh Shahbazi1,2, Manoochehr Karami1,3, Mohammad Mirzaei4
1Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
Insights
This study identified key risk factors for COVID-19 mortality in Iran. Elderly individuals, males, and those with comorbidities faced a higher risk of death, highlighting the need for targeted interventions.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Coronavirus disease 2019 (COVID-19) is a contagious illness with incompletely understood survival rates and prognostic factors.
- Understanding these factors is crucial for effective public health strategies and patient management.
Purpose of the Study:
- To identify risk factors associated with survival among COVID-19 patients.
- To analyze prognostic factors influencing COVID-19 outcomes in Hamadan province, Iran.
Main Methods:
- Retrospective cohort study conducted in Hamadan province, Iran (February 20 - September 20, 2020).
- Inclusion of patients referred to provincial hospitals, with follow-up from symptom onset to death.
- Statistical analysis using Kaplan-Meier method, Flemington-Harrington test, and Cox regression.
Main Results:
- Overall survival rates at 1, 5, 10, 20, 30, and 49 days were 99.57%, 95.61%, 91.15%, 87.34%, 86.91%, and 86.74%, respectively.
- Survival time was significantly associated with age, gender, travel history to contaminated areas, co-morbidities, neoplasms, chronic diseases, and hospital units.
Conclusions:
- Elderly individuals, males, and patients with comorbidities exhibited a significantly higher risk of mortality from COVID-19.
- Targeted attention and interventions for these high-risk groups are essential to mitigate COVID-19 incidence and consequences.
Background:
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a newly identified coronavirus. Our knowledge about the survival rate and prognostic factors of the disease is not established well. Therefore, this study aimed to identify the risk factors associated with the survival of COVID-19 cases in Hamadan province, West of Iran.
Study Design:
A retrospective cohort study METHODS: This retrospective cohort study was performed in Hamadan province, West of Iran. The study included patients that referred to the provincial hospitals from February 20 to September 20, 2020. The follow-up of each subject was calculated from the date of onset of respiratory symptoms to the date of death. Demographic and clinical characteristics were extracted from patients' medical records. Kaplan-Meier method, Flemington-Harrington test, and Cox regression were used for data analysis.
Results:
The overall 1, 5, 10, 20, 30 and 49-day survival rates were estimated at 99.57%, 95.61%, 91.15%, 87.34%, 86.91%, and 86.74%, respectively. Furthermore, survival time showed a significant association with age, gender, history of traveling to contaminated areas, co-morbidity, neoplasms, chronic diseases, and hospital units.
Conclusion:
In conclusion, elderly people, male gender, and comorbidities presented a greater risk of death. Therefore, it is important to pay more attention to this group of people to reduce the incidence and consequences after infection.
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