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The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
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Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds
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Which East Asian herbal medicines can decrease viral infections?

Kenny Kuchta1, Silke Cameron2, Minwon Lee3

  • 1Forschungsstelle Für Fernöstliche Medizin, Department of Vegetation Analysis and Phytodiversity, Albrecht Von Haller Institute of Plant Sciences, Georg August University, Göttingen, Germany.

Phytochemistry Reviews : Proceedings of the Phytochemical Society of Europe
|September 1, 2021
PubMed
Summary

East Asian traditional herbal remedies, including Maoto and Andrographis paniculata, show promise for treating COVID-19 by targeting viral entry and replication. These natural therapies offer potential alternatives to Western medicine for managing viral pandemics.

Keywords:
Andrographis paniculataCOVID-19Influenza virusKampoMaoto

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Area of Science:

  • Traditional East Asian Medicine
  • Phytotherapy
  • Virology

Background:

  • Western COVID-19 research prioritizes vaccination.
  • East Asian countries explore traditional herbal prescriptions for SARS-CoV-2 therapy.
  • Herbal remedies have demonstrated antiviral, immunomodulatory, and anti-inflammatory effects.

Purpose of the Study:

  • To provide an overview of East Asian herbal remedies for COVID-19 treatment.
  • To discuss the efficacy and mechanisms of these remedies.
  • To explore their potential in managing viral pandemics.

Main Methods:

  • Review of clinical evidence for herbal prescriptions.
  • Analysis of traditional herbal formulas used in East Asia.
  • Examination of mechanisms related to viral entry and replication.

Main Results:

  • Maoto, used for influenza, shows comparable effects to oseltamivir.
  • Andrographis paniculata extracts are approved in Thailand for COVID-19 treatment.
  • Maoto-ka-senshinren (combination of Maoto and Andrographis paniculata) appears promising.
  • Chinese TCM medications like Qing-Fei-Pai-Du-Tang and Shufeng Jiedu Jiaonang are included in official guidelines.
  • Fufang Yuxingcao Heiji gained prominence during the 2002 SARS epidemic.

Conclusions:

  • East Asian herbal remedies offer potential therapeutic strategies for COVID-19.
  • These natural treatments target key aspects of viral infection, including entry and replication.
  • Further research into these traditional medicines could provide valuable options for managing viral pandemics.