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Updated: Oct 22, 2025

LAD-Ligation: A Murine Model of Myocardial Infarction
Published on: October 14, 2009
Fulminant myocarditis secondary to murine typhus mimicking acute coronary syndrome
Dana Toy1, Christopher Vo1, Wilson C Kwan2
1Department of Medicine, University of Southern California, 2020 Zonal Ave, Suite 620, Los Angeles, CA 90089, USA.
Abstract:
Myocarditis is a disease with variable clinical presentation, ranging from an uncomplicated febrile illness to cardiogenic shock. Herein, we report a case of fulminant myocarditis secondary to murine typhus in a 52-year-old male that initially mimicked an acute coronary syndrome. Emergent coronary angiography showed angiographically normal coronary arteries. Left ventriculography showed global hypokinesis with an ejection fraction of 10%. The patient required mechanical support with an intra-aortic balloon pump and fully recovered. <Learning objective:Fulminant myocarditis secondary to murine typhus may occur in urban areas. Clinical complications such as cardiogenic shock and acute heart failure can be overcome with supportive therapy such as an intra-aortic balloon pump and guideline-directed medical therapy.>.
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