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Morphometric Study of Mitral Valve Annulus in Iran.
Tahereh Mohtaj1, Mathias H Aazami2,3, Ghassem Sazegar1,4
1Department of Cell Biology and Anatomy, School of Medicine, Medical Sciences University, Mashhad, Iran.
Galen Medical Journal
|September 1, 2021
Summary
This study determined normal mitral annulus (MA) dimensions in an Iranian population. Findings reveal specific MA measurements vary with age and gender, crucial for cardiac assessments.
Area of Science:
- Cardiovascular Anatomy
- Medical Imaging
- Human Physiology
Background:
- The mitral annulus (MA) is a critical structure in cardiac function.
- Understanding normal MA dimensions is essential for diagnosing and managing valvular heart disease.
- Previous studies have not comprehensively defined MA dimensions specific to the Iranian population.
Purpose of the Study:
- To establish normative data for mitral annulus dimensions in the Iranian population.
- To investigate the influence of demographic factors (age, gender, stature, weight) on MA dimensions.
- To provide a reference for accurate echocardiographic and surgical evaluations.
Main Methods:
- A cross-sectional study involving 88 fresh human cadaveric hearts.
- Detailed measurements of the mitral annulus and its components were performed.
- Statistical analysis using SPSS version 16 was employed to analyze the collected data.
Main Results:
- Mean values for anatomic area, perimeter, and inter-commissural distance were recorded.
- Significant differences in specific valve leaflet measurements (Strut-P1, Base-P2) were observed between age groups.
- No significant gender-based differences were found in overall valve leaflet measurements.
Conclusions:
- Mitral annulus dimensions, including A2-P3, A2-P1, anatomic perimeter, and area, showed correlations with gender.
- Age was associated with A2-P1, A2-P2, Strut-P1, and Base-P2 measurements.
- Body mass index influenced Base-P2 dimensions, highlighting its relevance in MA assessment.