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Whey Protein (Ma'aljobon) as a Complementary Therapy for Treatment of Attention-deficit/ Hyperactivity Disorder
Zeinab Mostajeran1, Seyed Hamdollah Mosavat2,3, Mostafa Najafi4
1Department of Persian Medicine, School of Persian Medicine, Shahid Sadoughi University of Medical Sciences, Ardakan, Yazd, Iran.
Insights
Ma'aljobon, a whey protein, may help manage symptoms of Attention Deficit Hyperactivity Disorder (ADHD) in children. This study found it reduced hyperactivity and improved attention when used alongside standard treatment.
Area of Science:
- Nutritional Neuroscience
- Pediatric Psychiatry
- Food Science
Background:
- Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder characterized by hyperactivity, inattention, and impulsivity.
- Ma'aljobon, a traditional whey protein product, is traditionally believed to offer immune modulation and potential neuropsychiatric benefits.
Purpose of the Study:
- To investigate the efficacy of Ma'aljobon as a complementary therapy for managing ADHD symptoms in children.
Main Methods:
- An 8-week open-label, randomized controlled trial involving 64 children diagnosed with ADHD.
- Participants received either Ma'aljobon (25g daily) plus standard conventional treatment (SCT) or SCT alone.
- Outcomes were assessed using the Strengths and Difficulties Questionnaire (SDQ) and Conners' Continuous Performance Test (CPT).
Main Results:
- The intervention group showed a significant reduction in parent-reported hyperactivity scores on the SDQ (P=0.04).
- Significant improvements in attention and focus were observed in the intervention group based on CPT results (P=0.01).
- No significant differences were found in other SDQ scales between the groups.
Conclusions:
- Ma'aljobon shows promise as an adjunctive treatment for enhancing hyperactivity control, attention, and focus in children with ADHD.
- Further research with larger sample sizes and longer durations is recommended for more robust conclusions.
Background:
Attention deficit hyperactivity disorder (ADHD) is a common, chronic, neurodevelopmental disorder that manifests in childhood with symptoms of hyperactivity, inattention, and impulsivity. Ma'aljobon (a kind of whey protein) that is derived from milk during cheese producing process is a popular dietary traditional product supposed to provide immune modulation and prevent neuropsychiatric disorder. We aimed to evaluate the efficacy of ma'aljobon in management of Attention-deficit/hyperactivity disorder (ADHD).
Materials And Methods:
In this open-label randomized, double arm, and controlled clinical trial, sixty four patients with ADHD who referred to out-patient child and adolescent clinic of Khorshid Hospital of Isfahan, Iran, were randomly assigned in the intervention group (ma'aljobon 25 g once daily plus standard conventional treatment (SCT)) or control group (SCT only) for a period of 8 weeks. Scores of the Strengths and Difficulties Questionnaire (SDQ) and Conners' Continuous Performance Test (CPT) were set as the outcome measures.
Results:
Parent reported hyperactivity scale of SDQ showed a significant decrease in the intervention group compared to the control group (P=0.04). However, no significant between groups differences were observed in other scales of parent-reported SDQ. Also, according to the results of CPT, there was a significant improvement in the intervention group regarding attention and focus score (P=0.01).
Conclusion:
Ma'aljobon might be considered as a complementary remedy for improving hyperactivity, attention and focus of children with ADHD. However, further researches with larger sample size and longer duration should be done for achieving more reliable results.
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