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[Research progress on chemical constituents and pharmacological activities of Trigonella foenum-graecum]
Yan-Feng He1, Hong-Ting Ma1, Rui-Nan Wang1
1College of Pharmacy, Qinghai University for Nationalities Xining 810007, China Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province Xining 810007, China.
Abstract:
Trigonella foenum-graecum is an annual plant of the genus Trigonella in the Leguminosae family. It is widely distributed in China and has a long history of application. According to phytochemistry research, the seeds, stem, and leaves of this herb contain not only a variety of bioactive ingredients, including alkaloids, saponins, polysaccharides, flavonoids, and phenols, but also abundant nutrients such as unsaturated fatty acids and amino acids and various trace elements. Pharmacological studies have shown that both the extract of T. foenum-graecum and its chemical constituents exhibit hypoglycemic, hypolipidemic, antitumor, antioxidative, antimicro-bial, and hepatoprotective activities. This paper reviews the research progress on the chemical constituents and pharmacological effects of T. foenum-graecum, which may contribute to further development, application, and clinical research of this herb.
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