Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Adrenergic Antagonists: ɑ and β-Receptor Blockers

Adrenergic Antagonists: ɑ and β-Receptor Blockers

Third-generation β-blockers, such as labetalol and carvedilol, represent a significant advancement in managing cardiovascular conditions. Unlike conventional β-blockers, which can induce peripheral vasoconstriction, third-generation drugs block α1 adrenoceptors. This promotes vasodilation through several mechanisms, such as increased nitric oxide production, inhibition of calcium ion entry, opening of potassium ion channels, and antioxidant action. Labetalol, for instance, is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Analysis of clinical characteristics of renal oncocytoma: 26 cases report].

Zhonghua wai ke za zhi [Chinese journal of surgery]·2012

Same author

[Expression of Na+/H+ antiporter gene KsNHX1 in Kochia sieversiana under saline-alkali stress].

Ying yong sheng tai xue bao = The journal of applied ecology·2012

Same author

Fasudil, a Rho-kinase inhibitor, attenuates bleomycin-induced pulmonary fibrosis in mice.

International journal of molecular sciences·2012

Same author

[Analysis of genes and genetic susceptibility of olfactory disorders].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2012

Same author

Top-down processing of symbolic meanings modulates the visual word form area.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2012

Same author

Oxidative stress acts on special membrane proteins to reduce the viability of Pseudomonas syringae pv tomato.

Journal of proteome research·2012

Search research articles

Related Experiment Video

Updated: Oct 21, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

[A new labdane-type diterpenoids from Callicarpa nudiflora].

Li-Li Zhan¹, Wei-Ming Huang¹, Yu-Ting Bian¹

¹School of Pharmacy, Jiangxi University of Chinese Medicine Nanchang 330004, China.

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica

|September 1, 2021

Summary

Researchers identified ten bioactive compounds from Callicarpa nudiflora leaves, including one new compound and several others new to the Callicarpa genus. This study enhances understanding of the plant

Keywords:

Callicarpa nudiflora chemical constituents diterpenoids phenylethanoid glycosides

More Related Videos

Author Spotlight: Integrating 2D-HPLC-MS and Molecular Networking in Natural Medicine Analysis

Author Spotlight: Integrating 2D-HPLC-MS and Molecular Networking in Natural Medicine Analysis

Published on: December 8, 2023

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Published on: March 8, 2024

Related Experiment Videos

Last Updated: Oct 21, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

Author Spotlight: Integrating 2D-HPLC-MS and Molecular Networking in Natural Medicine Analysis

Author Spotlight: Integrating 2D-HPLC-MS and Molecular Networking in Natural Medicine Analysis

Published on: December 8, 2023

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Published on: March 8, 2024

Area of Science:

Phytochemistry
Natural Product Chemistry
Pharmacognosy

Background:

Callicarpa nudiflora is a plant species with potential medicinal properties.
Investigating its chemical constituents is crucial for understanding its bioactivity.

Purpose of the Study:

To isolate and identify bioactive compounds from the leaves of Callicarpa nudiflora.
To characterize novel and previously unreported compounds within the Callicarpa genus.

Main Methods:

Extraction of C. nudiflora leaves using 65% ethanol.
Isolation of compounds using macroporous adsorption resin, Sephadex LH-20, ODS, silica gel, and preparative HPLC.
Structure elucidation using Nuclear Magnetic Resonance (NMR), High-Resolution Electrospray Ionization Mass Spectrometry (HR-ESI-MS), and optical rotation data.

Main Results:

Ten compounds were successfully isolated and identified.
Callicapene M6 was identified as a new compound.
Sterebin A and crenatoside were isolated from the Callicarpa genus for the first time.
(7R)-campneoside I and (7S)-campneoside I were isolated from C. nudiflora for the first time.

Conclusions:

The phytochemical investigation of Callicarpa nudiflora yielded ten compounds, including a novel one.
The study expands the known chemical diversity of the Callicarpa genus and C. nudiflora.
These findings provide a basis for further research into the pharmacological potential of these isolated compounds.