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[Neurological manifestations in pediatric patients with COVID-19: case report]
Sandra C Schult-Montoya1,2, Paola R Pichilingue-Torres1, Werner L Vásquez-Vidal1
1Instituto Nacional de Salud del Niño Breña, Lima, Perú.
Insights
The COVID-19 pandemic impacts children, causing diverse symptoms including neurological issues. This study details the spectrum of neurological effects of SARS-CoV-2 infection in pediatric patients.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- The COVID-19 pandemic affects all age groups, including children.
- Pediatric COVID-19 presents with a wide range of clinical symptoms.
- Neurological manifestations in children with COVID-19 require further characterization.
Observation:
- This report documents a series of pediatric cases with COVID-19.
- Clinical and neurological manifestations were observed during the disease's evolution.
- Observed neurological symptoms included seizures, muscle weakness, and sensory disorders.
Findings:
- SARS-CoV-2 can cause neurological injury through direct viral effects or immune responses.
- The clinical presentation of neurological involvement in pediatric COVID-19 is variable.
- Studies on pediatric COVID-19 neurological characteristics and prognosis are limited.
Implications:
- Understanding the spectrum of neurological manifestations is crucial for pediatric COVID-19 management.
- This case series contributes to the limited data on pediatric neurological complications of SARS-CoV-2.
- Further research is needed to elucidate mechanisms and prognostic factors of COVID-19-related neurological conditions in children.
Abstract:
The COVID-19 pandemic currently affects millions of people including the pediatric population. The clinical manifestations in children are diverse: respiratory, gastrointestinal, hematological, neurological and systemic. In order to describe the various clinical and neurological manifestations during the evolution of the disease, we documented a series of cases of pediatric patients with COVID-19. Various mechanisms are proposed through which SARS-CoV-2 would cause neurological injury (direct injury, secondary to an immune response, among others) with variable clinical characteristics (seizures, muscle weakness, sensorial disorder). Studies on clinical characteristics and prognostic factors in children and adolescents with SARS-CoV-2 are limited, therefore, this report provides a spectrum of neurological manifestations associated with SARS-CoV-2 in pediatric population.
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