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Related Experiment Video

Updated: Oct 21, 2025

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

Imaging Updates to Breast Cancer Lymph Node Management.

Hannah L Chung¹, Huong T Le-Petross¹, Jessica W T Leung¹

¹From the Department of Breast Imaging, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1350, Houston, TX 77030.

Radiographics : a Review Publication of the Radiological Society of North America, Inc

|September 1, 2021

Summary

Accurate staging of breast cancer lymph node metastasis is crucial. Imaging and image-guided interventions are now vital for assessing nodal involvement, guiding neoadjuvant systemic treatment (NST), and determining surgical approaches.

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Area of Science:

Oncology
Radiology
Surgical Pathology

Background:

Lymph node status is critical for breast cancer staging and prognosis.
Historically, surgical pathology determined treatment, but neoadjuvant systemic treatment (NST) is increasingly used first.
NST may allow for less radical surgery if a good therapeutic response is observed.

Purpose of the Study:

To review the role of imaging and image-guided interventions in assessing breast cancer lymph node metastasis.
To discuss how imaging guides treatment decisions, monitors response to NST, and influences surgical planning.
To emphasize the importance of imaging within a multidisciplinary approach to breast cancer care.

Main Methods:

Review of imaging features of nodal metastases.

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Last Updated: Oct 21, 2025

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Discussion of indications and techniques for image-guided lymph node procedures.

Evaluation of the utility and limitations of various imaging modalities for lymph node assessment, especially when biopsy results are unavailable.

Main Results:

Imaging can evaluate all regional nodal basins, aiding in the decision between surgical or medical initial treatment.
Imaging monitors in vivo nodal response to NST, informing subsequent surgical technique.
Imaging findings are essential for tailoring treatment and surgical strategies post-NST.

Conclusions:

Imaging and image-guided procedures are increasingly important for lymph node assessment in breast cancer, especially with the rise of NST.
These imaging techniques support a multidisciplinary approach by providing crucial information for treatment planning and monitoring.
A comprehensive understanding of imaging features and guided procedures is vital for optimal breast cancer management.