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Racial Differences in Blood Pressure Control Following Stroke: The REGARDS Study
Oluwasegun P Akinyelure1, Byron C Jaeger2, Tony L Moore1
1Department of Epidemiology, School of Public Health (O.P.A., T.L.M., D.H., V.J.H., P.M.), University of Alabama at Birmingham.
Insights
Black adults, with or without stroke history, had lower blood pressure control rates than White adults. This disparity persisted even after adjusting for other health factors, highlighting a need for targeted interventions.
Area of Science:
- Cardiovascular Health
- Health Disparities
- Stroke Prevention
Background:
- Black adults face higher risks of uncontrolled blood pressure (BP) and stroke compared to White adults.
- High BP is a significant risk factor for recurrent stroke, yet racial disparities in BP control among stroke survivors are understudied.
Purpose of the Study:
- To investigate racial differences in BP control between Black and White adults.
- To examine these disparities in both stroke survivors and individuals without a history of stroke.
Main Methods:
- Utilized data from the REGARDS study (Reasons for Geographic and Racial Differences in Stroke).
- Analyzed participants on antihypertensive medication, comparing BP control at a second visit (2013-2016) based on stroke history (n=306 with stroke, n=7693 without).
- Defined BP control as systolic BP <130 mmHg and diastolic BP <80 mmHg, with specific criteria for older adults (≥65 years).
Main Results:
- Among participants with a history of stroke, 39.3% of Black adults had controlled BP versus 50.3% of White adults.
- Among participants without a history of stroke, 50.2% of Black adults had controlled BP versus 56.0% of White adults.
- Multivariable adjustment showed a trend towards lower BP control in Black participants (PR=0.77 for stroke survivors, PR=0.92 for non-stroke participants).
Conclusions:
- A lower proportion of Black adults achieved controlled blood pressure compared to White adults, irrespective of stroke history.
- Statistical analysis indicated no significant racial disparities in BP control after adjusting for multiple factors.
Background And Purpose:
In the general population, Black adults are less likely than White adults to have controlled blood pressure (BP), and when not controlled, they are at greater risk for stroke compared with White adults. High BP is a major modifiable risk factor for recurrent stroke, but few studies have examined racial differences in BP control among stroke survivors.
Methods:
We used data from the REGARDS study (Reasons for Geographic and Racial Differences in Stroke) to examine disparities in BP control between Black and White adults, with and without a history of stroke. We studied participants taking antihypertensive medication who did and did not experience an adjudicated stroke (n=306 and 7693 participants, respectively) between baseline (2003-2007) and a second study visit (2013-2016). BP control at the second study visit was defined as systolic BP <130 mm Hg and diastolic BP <80 mm Hg except for low-risk adults ≥65 years of age (ie, those without diabetes, chronic kidney disease, history of cardiovascular disease, and with a 10-year predicted atherosclerotic cardiovascular disease risk <10%) for whom BP control was defined as systolic BP <130 mm Hg.
Results:
Among participants with a history of stroke, 50.3% of White compared with 39.3% of Black participants had controlled BP. Among participants without a history of stroke, 56.0% of White compared with 50.2% of Black participants had controlled BP. After multivariable adjustment, there was a tendency for Black participants to be less likely than White participants to have controlled BP (prevalence ratio, 0.77 [95% CI, 0.59-1.02] for those with a history of stroke and 0.92 [95% CI, 0.88-0.97] for those without a history of stroke).
Conclusions:
There was a lower proportion of controlled BP among Black compared with White adults with or without stroke, with no statistically significant differences after multivariable adjustment.
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