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Updated: Oct 21, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Comparative Effectiveness of Clinical and Community-Based Approaches to Healthy Weight
Lauren Fiechtner1,2, Meghan Perkins3, Vincent Biggs4
1Division of General Academic Pediatrics, Department of Pediatrics, Massachusetts General Hospital for Children, Boston, Massachusetts lfiechtner@mgh.harvard.edu.
Insights
The Healthy Weight Clinic (HWC) effectively reduced BMI in Hispanic children, while the modified Healthy Weight and Your Child (M-HWYC) intervention did not show significant results. HWC offers a promising pediatric weight management solution.
Area of Science:
- Pediatric Endocrinology
- Public Health Nutrition
- Behavioral Medicine
Background:
- Childhood obesity, particularly among low-income Hispanic populations, presents a significant public health challenge.
- Effective, accessible interventions are crucial for managing pediatric weight and preventing associated comorbidities.
- Existing pediatric weight management programs require evaluation for efficacy in diverse, underserved communities.
Purpose of the Study:
- To compare the effectiveness of two pediatric weight management interventions in reducing Body Mass Index (BMI) among Hispanic children.
- To evaluate if a health center-based Healthy Weight Clinic (HWC) is non-inferior to a community-based modified Healthy Weight and Your Child (M-HWYC) program.
- To assess the impact of these interventions on BMI and BMI percentile changes in a low-income pediatric population.
Main Methods:
- A randomized controlled trial involving 407 Hispanic children (aged 6-12 years) with BMI at or above the 85th percentile.
- Interventions included a Healthy Weight Clinic (HWC) at a health center and a modified Healthy Weight and Your Child (M-HWYC) program at a Young Men's Christian Association (YMCA).
- Non-inferiority testing was conducted by comparing the change in %BMIp95 between interventions, with a comparison group of 4037 children used for yearly BMI change analysis.
Main Results:
- The M-HWYC intervention was not found to be non-inferior to the HWC, with a mean difference in %BMIp95 of 0.75 (90% CI: 0.07 to 1.43).
- Children in the HWC showed a statistically significant decrease in BMI (-0.23 per year) and %BMIp95 (-1.03 per year) compared to the comparison sites.
- No significant BMI changes were observed in children participating in the M-HWYC intervention.
Conclusions:
- The modified Healthy Weight and Your Child (M-HWYC) intervention failed to demonstrate non-inferiority to the Healthy Weight Clinic (HWC).
- The HWC intervention proved effective in improving BMI among participating children, suggesting it is a viable treatment option.
- The findings highlight the HWC as an effective strategy for pediatric weight management, particularly for disproportionately affected populations.
Objectives:
The objective was to evaluate if 2 pediatric weight management interventions delivered to Hispanic, low-income children (one in a health center the other in a Young Men's Christian Association) were effective in reducing BMI. We hypothesized that they would be equally effective.
Methods:
A total 407 children aged 6 to 12 years with BMI ≥ 85th percentile receiving care at 2 health centers were randomly assigned to a healthy weight clinic (HWC) at the health center or to a modified Healthy Weight and Your Child (M-HWYC) intervention delivered in Young Men's Christian Associations. A total of 4037 children served as the comparison group. We completed a noninferiority test comparing the M-HWYC with the HWC, which was supported if the bounds of the 90% confidence interval (CI) for the difference in percentage of the 95th percentile (%BMIp95) change did not contain what we considered a minimally clinically important difference, on the basis of previous data (0.87). Then, using linear mixed models, we assessed yearly changes in BMI among intervention participants compared with the comparison sites.
Results:
The mean difference in %BMIp95 between the M-HWYC and the HWC was 0.75 (90% CI: 0.07 to 1.43), which did not support noninferiority. Compared with the comparison sites, per year, children in the HWC had a -0.23 (95% CI: -0.36 to -0.10) decrease in BMI and a -1.03 (95% CI -1.61 to -0.45) %BMIp95 decrease. There was no BMI effect in the M-HWYC.
Conclusions:
We were unable to establish noninferiority of the M-HWYC. The HWC improved BMI, offering an effective treatment of those disproportionately affected.
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