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Related Concept Videos

Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

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Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
289
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
143
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
92
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

99
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
99
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

107
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Kidney Outcomes in Long COVID.

Benjamin Bowe1,2,3, Yan Xie1,2,3, Evan Xu1,4

  • 1Clinical Epidemiology Center, Research and Development Service, Veterans Affairs Saint Louis Health Care System, Saint Louis, Missouri.

Journal of the American Society of Nephrology : JASN
|September 2, 2021
PubMed
Summary

COVID-19 survivors face a higher risk of kidney damage, including acute kidney injury and long-term decline in kidney function. Post-COVID care must prioritize monitoring and addressing these kidney outcomes.

Keywords:
COVID-19ESKDESRDPASCacute kidney injuryeGFR declinekidney functionlong COVIDpost-acute COVIDpost-acute sequelae of SARS-CoV-2 infection

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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Public Health

Background:

  • Long COVID, or post-acute sequelae of COVID-19, affects multiple organ systems.
  • Kidney outcomes in long COVID patients have not been extensively studied.

Purpose of the Study:

  • To assess the risk of kidney outcomes in 30-day survivors of COVID-19.
  • To evaluate the association between COVID-19 severity and post-acute kidney disease.

Main Methods:

  • A cohort of 1,726,683 US Veterans was analyzed, including 89,216 COVID-19 survivors and 1,637,467 controls.
  • Risks of acute kidney injury (AKI), eGFR decline, end-stage kidney disease (ESKD), and major adverse kidney events (MAKE) were examined.
  • Inverse probability-weighted survival regression and linear mixed models were employed for analysis.

Main Results:

  • COVID-19 survivors showed significantly higher risks of AKI, eGFR decline (≥30%, ≥40%, ≥50%), ESKD, and MAKE compared to controls.
  • The risk of adverse kidney outcomes increased with the severity of acute COVID-19 infection (non-hospitalized, hospitalized, ICU).
  • Excess eGFR decline was observed in survivors, with greater decline in those with more severe acute infections.

Conclusions:

  • COVID-19 survivors have an elevated risk of kidney disease in the post-acute phase.
  • Routine screening for kidney disease is recommended for individuals recovering from COVID-19.
  • Integrating kidney disease monitoring into post-COVID-19 care strategies is crucial.